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E2F3 upregulation promotes tumor malignancy through the transcriptional activation of HIF-2α in clear cell renal cell carcinoma

The E2F3 transcriptional regulatory pathway plays a major part in multiple-cancer progression, but the specific contributions of this pathway to tumor formation and the progression of clear cell renal cell carcinoma (ccRCC) are not fully understood. Clinically, we demonstrated that E2F3 was overexpr...

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Detalles Bibliográficos
Autores principales: Gao, Yu, Li, Hongzhao, Ma, Xin, Fan, Yang, Ni, Dong, Zhang, Yu, Huang, Qingbo, Liu, Kan, Li, Xintao, Wang, Lei, Yao, Yuanxin, Ai, Qing, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589559/
https://www.ncbi.nlm.nih.gov/pubmed/28903320
http://dx.doi.org/10.18632/oncotarget.10568