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CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling

CD164 is a cell adhesion molecule that increases hematopoietic stem cell proliferation, adhesion, and migration via C-X-C chemokine receptor type 4 (CXCR4) signaling. Emerging evidence indicates that elevated CD164 expression is associated with aggressive metastasis, advanced stages, and shorter ove...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Liang, Huang, Ai-Fang, Huang, Shih-Ming, Ho, Ching-Liang, Chang, Yung-Lung, Chan, James Yi-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589567/
https://www.ncbi.nlm.nih.gov/pubmed/28903328
http://dx.doi.org/10.18632/oncotarget.11132