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CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling
CD164 is a cell adhesion molecule that increases hematopoietic stem cell proliferation, adhesion, and migration via C-X-C chemokine receptor type 4 (CXCR4) signaling. Emerging evidence indicates that elevated CD164 expression is associated with aggressive metastasis, advanced stages, and shorter ove...
Autores principales: | Chen, Wei-Liang, Huang, Ai-Fang, Huang, Shih-Ming, Ho, Ching-Liang, Chang, Yung-Lung, Chan, James Yi-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589567/ https://www.ncbi.nlm.nih.gov/pubmed/28903328 http://dx.doi.org/10.18632/oncotarget.11132 |
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