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Fractalkine/CX3CL1 induced intercellular adhesion molecule-1-dependent tumor metastasis through the CX3CR1/PI3K/Akt/NF-κB pathway in human osteosarcoma

Osteosarcoma is the most common primary bone tumor in children and teens. The exact molecular mechanism underlying osteosarcoma progression still remains unclear. The CX3CL1/fractalkine has been implicated in various tumors but not in osteosarcoma. This study is the first to show that fractalkine pr...

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Detalles Bibliográficos
Autores principales: Liu, Ju-Fang, Tsao, Ya-Ting, Hou, Chun-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589568/
https://www.ncbi.nlm.nih.gov/pubmed/28903329
http://dx.doi.org/10.18632/oncotarget.11250