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KIF7 attenuates prostate tumor growth through LKB1-mediated AKT inhibition

This study investigated kinesin family member 7 (KIF7) expression and function in prostate cancer (PCa). Our results showed that KIF7 was significantly downregulated in PCa, compared with normal, benign prostatic hyperplasia and prostate intraepithelial neoplasia tissues, partially through promoter...

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Detalles Bibliográficos
Autores principales: Wong, Kai Yau, Liu, Jing, Chan, Kwok Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589603/
https://www.ncbi.nlm.nih.gov/pubmed/28903364
http://dx.doi.org/10.18632/oncotarget.17421