Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Autophagy is a lysosomal degradation and recycling process implicated in cancer progression and therapy resistance. We assessed the impact of basal autophagy in colon cancer (CC) in vitro and ex vivo. Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent incre...

Descripción completa

Detalles Bibliográficos
Autores principales: Niklaus, Monique, Adams, Olivia, Berezowska, Sabina, Zlobec, Inti, Graber, Franziska, Slotta-Huspenina, Julia, Nitsche, Ulrich, Rosenberg, Robert, Tschan, Mario P., Langer, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589607/
https://www.ncbi.nlm.nih.gov/pubmed/28903368
http://dx.doi.org/10.18632/oncotarget.17554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589607/
https://www.ncbi.nlm.nih.gov/pubmed/28903368
http://dx.doi.org/10.18632/oncotarget.17554

Ejemplares similares