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Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer
Autophagy is a lysosomal degradation and recycling process implicated in cancer progression and therapy resistance. We assessed the impact of basal autophagy in colon cancer (CC) in vitro and ex vivo. Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent incre...
Autores principales: | Niklaus, Monique, Adams, Olivia, Berezowska, Sabina, Zlobec, Inti, Graber, Franziska, Slotta-Huspenina, Julia, Nitsche, Ulrich, Rosenberg, Robert, Tschan, Mario P., Langer, Rupert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589607/ https://www.ncbi.nlm.nih.gov/pubmed/28903368 http://dx.doi.org/10.18632/oncotarget.17554 |
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