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Tumor location impacts immune response in mouse models of colon cancer
Existing preclinical models of human colorectal cancer (CRC) that rely on syngeneic subcutaneous grafts are problematic, because of increasing evidence that the immune microenvironment in subcutaneous tissue is significantly different from the gastrointestinal tract. Similarly, existing orthotopic m...
Autores principales: | Zhao, Xianda, Li, Lihua, Starr, Timothy K., Subramanian, Subbaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589620/ https://www.ncbi.nlm.nih.gov/pubmed/28903381 http://dx.doi.org/10.18632/oncotarget.18423 |
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