Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro

Transendothelial cell migration (TEM) is crucial for inflammation and metastasis. The adhesion molecule CD99 was shown to be important for correct immune cell extravasation and is highly expressed on certain cancer cells. Recently, we demonstrated that ectodomain shedding of CD99 by the metalloprote...

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Detalles Bibliográficos
Autores principales: Bedau, Tillmann, Schumacher, Neele, Peters, Florian, Prox, Johannes, Arnold, Philipp, Koudelka, Tomas, Helm, Ole, Schmidt, Frederike, Rabe, Björn, Jentzsch, Marlene, Rosenstiel, Philip, Sebens, Susanne, Tholey, Andreas, Rose-John, Stefan, Becker-Pauly, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589627/
https://www.ncbi.nlm.nih.gov/pubmed/28903388
http://dx.doi.org/10.18632/oncotarget.18966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589627/
https://www.ncbi.nlm.nih.gov/pubmed/28903388
http://dx.doi.org/10.18632/oncotarget.18966

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