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Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

Circadian rhythms are regulated by transcriptional and post-translational feedback loops generated by appropriate functions of clock proteins. Rhythmic degradation of the circadian clock proteins is critical for maintenance of the circadian oscillations. Notably, circadian clock does not work during...

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Detalles Bibliográficos
Autores principales: Lu, Yilu, Zheng, Xulei, Hu, Wei, Bian, Shasha, Zhang, Zhiwei, Tao, Dachang, Liu, Yunqiang, Ma, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589630/
https://www.ncbi.nlm.nih.gov/pubmed/28903391
http://dx.doi.org/10.18632/oncotarget.18973