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Acute atorvastatin treatment restores the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats

BACKGROUND: Ischemic Postconditioning (IPC) reduces ischemia/reperfusion (I/R) injury under normal conditions. HMG-CoA reductase inhibitors (statins), which inhibit the synthesis of mevalonate, can interfere with the cardioprotective effect of IPC. However, the beneficial role of IPC in hyperlipidem...

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Detalles Bibliográficos
Autores principales: Sun, Tao, Zhang, Hong-Ju, Krittanawong, Chayakrit, Wang, Su, Tao, Ying, Li, Zhao, Yin, Qiancheng, Zhang, Donghua, Wang, Qian, Huang, Ji, Zhang, Jingmei, Li, Zhizhong, Cheng, Yutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589651/
https://www.ncbi.nlm.nih.gov/pubmed/28903412
http://dx.doi.org/10.18632/oncotarget.19232