A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome

Lynch syndrome (LS) is one of the most common familial forms of colorectal cancer predisposing syndrome with an autosomal dominant mode of inheritance. LS is caused by the germline mutations in DNA mismatch repair (MMR) genes including MSH2, MLH1, MSH6 and PMS2. Clinically, LS is characterized by hi...

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Detalles Bibliográficos
Autores principales: Wu, Bin, Ji, Wuyang, Liang, Shengran, Ling, Chao, You, Yan, Xu, Lai, Zhong, Min-Er, Xiao, Yi, Qiu, Hui-Zhong, Lu, Jun-Yang, Banerjee, Santasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589652/
https://www.ncbi.nlm.nih.gov/pubmed/28903413
http://dx.doi.org/10.18632/oncotarget.19234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589652/
https://www.ncbi.nlm.nih.gov/pubmed/28903413
http://dx.doi.org/10.18632/oncotarget.19234

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