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Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection
Aberrant DNA hypermethylation is a major epigenetic mechanism to inactivate tumor suppressor genes in cancer. Epstein-Barr virus positive gastric cancer is the most frequently hypermethylated tumor among human malignancies. Herein, we performed comprehensive analysis of epigenomic alteration during...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589657/ https://www.ncbi.nlm.nih.gov/pubmed/28903418 http://dx.doi.org/10.18632/oncotarget.19423 |