Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation

Genetically engineered animal tumor models have traditionally been generated by the gain of single or multiple oncogenes or the loss of tumor suppressor genes; however, the development of live animal models has been difficult given that cancer phenotypes are generally induced by somatic mutation rat...

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Detalles Bibliográficos
Autores principales: Shim, Jaegal, Choi, Jung-Hwa, Park, Moon-Hak, Kim, Hyena, Kim, Jong Hwan, Kim, Seon-Young, Hong, Dongwan, Kim, Sunshin, Lee, Ji Eun, Kim, Cheol-Hee, Lee, Jeong-Soo, Bae, Young-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589658/
https://www.ncbi.nlm.nih.gov/pubmed/28903419
http://dx.doi.org/10.18632/oncotarget.19424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589658/
https://www.ncbi.nlm.nih.gov/pubmed/28903419
http://dx.doi.org/10.18632/oncotarget.19424

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