CDK4/6 inhibition is more active against the glioblastoma proneural subtype

Glioblastoma (GBM) is the most common and lethal brain tumor. Gene expression profiling has classified GBM into distinct subtypes, including proneural, mesenchymal, and classical, and identifying therapeutic vulnerabilities of these subtypes is an extremely high priority. We leveraged The Cancer Gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ming, Xiao, Aizhen, Floyd, Desiree, Olmez, Inan, Lee, Jeongwu, Godlewski, Jakub, Bronisz, Agnieszka, Bhat, Krishna P.L., Sulman, Erik P., Nakano, Ichiro, Purow, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589661/
https://www.ncbi.nlm.nih.gov/pubmed/28903422
http://dx.doi.org/10.18632/oncotarget.19429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589661/
https://www.ncbi.nlm.nih.gov/pubmed/28903422
http://dx.doi.org/10.18632/oncotarget.19429

Ejemplares similares