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CDK4/6 inhibition is more active against the glioblastoma proneural subtype
Glioblastoma (GBM) is the most common and lethal brain tumor. Gene expression profiling has classified GBM into distinct subtypes, including proneural, mesenchymal, and classical, and identifying therapeutic vulnerabilities of these subtypes is an extremely high priority. We leveraged The Cancer Gen...
Autores principales: | Li, Ming, Xiao, Aizhen, Floyd, Desiree, Olmez, Inan, Lee, Jeongwu, Godlewski, Jakub, Bronisz, Agnieszka, Bhat, Krishna P.L., Sulman, Erik P., Nakano, Ichiro, Purow, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589661/ https://www.ncbi.nlm.nih.gov/pubmed/28903422 http://dx.doi.org/10.18632/oncotarget.19429 |
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