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CG200745, an HDAC inhibitor, induces anti-tumour effects in cholangiocarcinoma cell lines via miRNAs targeting the Hippo pathway

Cholangiocarcinoma is a devastating malignancy with fatal complications that exhibits low response and resistance to chemotherapy. Here, we evaluated the anticancer effects of CG200745, a novel histone deacetylase inhibitor, either alone or in combination with standard chemotherapy drugs in cholangi...

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Detalles Bibliográficos
Autores principales: Jung, Dawoon E., Park, Soo Been, Kim, Kahee, Kim, Chanyang, Song, Si Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589721/
https://www.ncbi.nlm.nih.gov/pubmed/28883618
http://dx.doi.org/10.1038/s41598-017-11094-3