Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome

Factor (F) Xa reactive IgG isolated from patients with antiphospholipid syndrome (APS) display higher avidity binding to FXa with greater coagulant effects compared to systemic lupus erythematosus (SLE) non APS IgG. FXa signalling via activation of protease-activated receptors (PAR) leads to increas...

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Detalles Bibliográficos
Autores principales: Artim-Esen, Bahar, Smoktunowicz, Natalia, McDonnell, Thomas, Ripoll, Vera M., Pericleous, Charis, Mackie, Ian, Robinson, Eifion, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Chambers, Rachel C., Giles, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589732/
https://www.ncbi.nlm.nih.gov/pubmed/28883515
http://dx.doi.org/10.1038/s41598-017-11315-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589732/
https://www.ncbi.nlm.nih.gov/pubmed/28883515
http://dx.doi.org/10.1038/s41598-017-11315-9

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