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T cells display mitochondria hyperpolarization in human type 1 diabetes

T lymphocytes constitute a major effector cell population in autoimmune type 1 diabetes. Despite essential functions of mitochondria in regulating activation, proliferation, and apoptosis of T cells, little is known regarding T cell metabolism in the progression of human type 1 diabetes. In this stu...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Chernatynskaya, Anna V., Li, Jian-Wei, Kimbrell, Matthew R., Cassidy, Richard J., Perry, Daniel J., Muir, Andrew B., Atkinson, Mark A., Brusko, Todd M., Mathews, Clayton E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589742/
https://www.ncbi.nlm.nih.gov/pubmed/28883439
http://dx.doi.org/10.1038/s41598-017-11056-9