Cargando…
T cells display mitochondria hyperpolarization in human type 1 diabetes
T lymphocytes constitute a major effector cell population in autoimmune type 1 diabetes. Despite essential functions of mitochondria in regulating activation, proliferation, and apoptosis of T cells, little is known regarding T cell metabolism in the progression of human type 1 diabetes. In this stu...
Autores principales: | Chen, Jing, Chernatynskaya, Anna V., Li, Jian-Wei, Kimbrell, Matthew R., Cassidy, Richard J., Perry, Daniel J., Muir, Andrew B., Atkinson, Mark A., Brusko, Todd M., Mathews, Clayton E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589742/ https://www.ncbi.nlm.nih.gov/pubmed/28883439 http://dx.doi.org/10.1038/s41598-017-11056-9 |
Ejemplares similares
-
2431: Characterization of immune cell differences with anti-thymocyte globulin (ATG) and granulocyte colony stimulating factor (GCSF) in both preclinical and clinical models of type 1 diabetes
por: Lin, Andrea, et al.
Publicado: (2018) -
Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling
por: Perry, Daniel J., et al.
Publicado: (2018) -
Human immune phenotyping reveals accelerated aging in type 1 diabetes
por: Shapiro, Melanie R., et al.
Publicado: (2023) -
Type 1 Interferons Potentiate Human CD8(+) T-Cell Cytotoxicity Through a STAT4- and Granzyme B–Dependent Pathway
por: Newby, Brittney N., et al.
Publicado: (2017) -
Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes
por: Xue, Song, et al.
Publicado: (2015)