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Antibody production by in vivo RNA transfection

Monoclonal antibodies have a variety of applications in research and medicine. Here, we report development of a new method for production of monoclonal antibodies. Our method relies on in vivo RNA transfection rather than peptide vaccination. We took advantage of RNA transcripts complexed with DOTMA...

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Detalles Bibliográficos
Autores principales: Romani, Bizhan, Kavyanifard, Amirarsalan, Allahbakhshi, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589809/
https://www.ncbi.nlm.nih.gov/pubmed/28883620
http://dx.doi.org/10.1038/s41598-017-11399-3