Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells

Atypical antipsychotics (AAPs) are considered to possess superior efficacy for treating both the positive and negative symptoms of schizophrenia; however, AAP use often causes excessive weight gain and metabolic abnormalities. Recently, several reports have demonstrated that AAPs activate sterol reg...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Chih, Hsu, Li-Wen, Huang, Kuang-Tzu, Goto, Shigeru, Chen, Chao-Long, Nakano, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589828/
https://www.ncbi.nlm.nih.gov/pubmed/28883496
http://dx.doi.org/10.1038/s41598-017-11323-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589828/
https://www.ncbi.nlm.nih.gov/pubmed/28883496
http://dx.doi.org/10.1038/s41598-017-11323-9

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