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Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells

Atypical antipsychotics (AAPs) are considered to possess superior efficacy for treating both the positive and negative symptoms of schizophrenia; however, AAP use often causes excessive weight gain and metabolic abnormalities. Recently, several reports have demonstrated that AAPs activate sterol reg...

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Detalles Bibliográficos
Autores principales:	Chen, Chien-Chih, Hsu, Li-Wen, Huang, Kuang-Tzu, Goto, Shigeru, Chen, Chao-Long, Nakano, Toshiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589828/ https://www.ncbi.nlm.nih.gov/pubmed/28883496 http://dx.doi.org/10.1038/s41598-017-11323-9

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