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BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts

Dentin sialophosphoprotein (Dspp) as a differentiation marker of odontoblasts is regulated by BMP-2. However, the intimate mechanism is still unknown. Transcription factors Dlx3 and Osx are essential for odontoblasts differentiation. We hypothesized that BMP-2 regulation of Dspp transcription was me...

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Detalles Bibliográficos
Autores principales: Yang, Guobin, Yuan, Guohua, MacDougall, Mary, Zhi, Chen, Chen, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589848/
https://www.ncbi.nlm.nih.gov/pubmed/28883412
http://dx.doi.org/10.1038/s41598-017-10908-8