Global fibroblast activation throughout the left ventricle but localized fibrosis after myocardial infarction

Fibroblast (Fb) differentiation and interstitial fibrosis contribute to cardiac remodeling and loss of function after myocardial infarction (MI). We investigated regional presence and regulation of fibrosis in a pig MI model. In vivo analysis of regional function and perfusion defined three regions:...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagaraju, Chandan K., Dries, Eef, Popovic, Natasa, Singh, Abhishek A., Haemers, Peter, Roderick, H. Llewelyn, Claus, Piet, Sipido, Karin R., Driesen, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589875/
https://www.ncbi.nlm.nih.gov/pubmed/28883544
http://dx.doi.org/10.1038/s41598-017-09790-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589875/
https://www.ncbi.nlm.nih.gov/pubmed/28883544
http://dx.doi.org/10.1038/s41598-017-09790-1

Ejemplares similares