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Global fibroblast activation throughout the left ventricle but localized fibrosis after myocardial infarction
Fibroblast (Fb) differentiation and interstitial fibrosis contribute to cardiac remodeling and loss of function after myocardial infarction (MI). We investigated regional presence and regulation of fibrosis in a pig MI model. In vivo analysis of regional function and perfusion defined three regions:...
Autores principales: | Nagaraju, Chandan K., Dries, Eef, Popovic, Natasa, Singh, Abhishek A., Haemers, Peter, Roderick, H. Llewelyn, Claus, Piet, Sipido, Karin R., Driesen, Ronald B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589875/ https://www.ncbi.nlm.nih.gov/pubmed/28883544 http://dx.doi.org/10.1038/s41598-017-09790-1 |
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