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Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients
Hundreds of genetic loci participate to schizophrenia liability. It is also known that impaired cerebral connectivity is directly related to the cognitive and affective disturbances in schizophrenia. How genetic susceptibility and brain neural networks interact to specify a pathological phenotype in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589880/ https://www.ncbi.nlm.nih.gov/pubmed/28883405 http://dx.doi.org/10.1038/s41537-017-0027-3 |