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Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients

Hundreds of genetic loci participate to schizophrenia liability. It is also known that impaired cerebral connectivity is directly related to the cognitive and affective disturbances in schizophrenia. How genetic susceptibility and brain neural networks interact to specify a pathological phenotype in...

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Detalles Bibliográficos
Autores principales: Ibrahim, El Chérif, Guillemot, Vincent, Comte, Magali, Tenenhaus, Arthur, Zendjidjian, Xavier Yves, Cancel, Aida, Belzeaux, Raoul, Sauvanaud, Florence, Blin, Olivier, Frouin, Vincent, Fakra, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589880/
https://www.ncbi.nlm.nih.gov/pubmed/28883405
http://dx.doi.org/10.1038/s41537-017-0027-3