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β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction

COPD is characterised by poorly reversible airflow obstruction usually due to cigarette smoking. The transcription factor clusters of β-catenin/Snail1/Twist has been implicated in the process of epithelial mesenchymal transition (EMT), an intermediate between smoking and airway fibrosis, and indeed...

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Detalles Bibliográficos
Autores principales: Mahmood, Malik Quasir, Walters, Eugene Haydn, Shukla, Shakti D., Weston, Steve, Muller, Hans Konrad, Ward, Chris, Sohal, Sukhwinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589881/
https://www.ncbi.nlm.nih.gov/pubmed/28883453
http://dx.doi.org/10.1038/s41598-017-11375-x