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β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction
COPD is characterised by poorly reversible airflow obstruction usually due to cigarette smoking. The transcription factor clusters of β-catenin/Snail1/Twist has been implicated in the process of epithelial mesenchymal transition (EMT), an intermediate between smoking and airway fibrosis, and indeed...
Autores principales: | Mahmood, Malik Quasir, Walters, Eugene Haydn, Shukla, Shakti D., Weston, Steve, Muller, Hans Konrad, Ward, Chris, Sohal, Sukhwinder Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589881/ https://www.ncbi.nlm.nih.gov/pubmed/28883453 http://dx.doi.org/10.1038/s41598-017-11375-x |
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