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MITF and BRN2 contribute to metastatic growth after dissemination of melanoma

Melanoma tumors are highly heterogeneous, comprising of different cell types that vary in their potential for growth and invasion. Heterogeneous expression of the Microphthalmia-associated Transcription Factor (MITF) and the POU domain transcription factor BRN2 (POU3F2) has been found in malignant m...

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Detalles Bibliográficos
Autores principales: Simmons, Jacinta L., Pierce, Carly J., Al-Ejeh, Fares, Boyle, Glen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589904/
https://www.ncbi.nlm.nih.gov/pubmed/28883623
http://dx.doi.org/10.1038/s41598-017-11366-y