CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons

CAPS (calcium-dependent activator protein for secretion) are multi-domain proteins involved in regulated exocytosis of synaptic vesicles (SVs) and dense core vesicles (DCVs). Here, we assessed the contribution of different CAPS-1 domains to its subcellular localization and DCV exocytosis by expressi...

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Detalles Bibliográficos
Autores principales: van Keimpema, Linda, Kooistra, Robbelien, Toonen, Ruud F., Verhage, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589909/
https://www.ncbi.nlm.nih.gov/pubmed/28883501
http://dx.doi.org/10.1038/s41598-017-10936-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589909/
https://www.ncbi.nlm.nih.gov/pubmed/28883501
http://dx.doi.org/10.1038/s41598-017-10936-4

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