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Insight into synergetic mechanisms of tetracycline and the selective serotonin reuptake inhibitor, sertraline, in a tetracycline-resistant strain of Escherichia coli

Sertraline, an antidepressive drug, has been reported to inhibit general bacterial efflux pumps. In the present study, we report for the first time a synergistic effect of sertraline and tetracycline in a TetA-encoded tetracycline-resistant strain of Escherichia coli. Synergy between sertraline and...

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Detalles Bibliográficos
Autores principales: Li, Lili, Kromann, Sofie, Olsen, John Elmerdahl, Svenningsen, Søren Wedel, Olsen, Rikke Heidemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589974/
https://www.ncbi.nlm.nih.gov/pubmed/28698674
http://dx.doi.org/10.1038/ja.2017.78