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miR-125b predicts childhood acute lymphoblastic leukaemia poor response to BFM chemotherapy treatment

BACKGROUND: Despite the favourable survival rates of childhood acute lymphoblastic leukaemia (ALL), a significant number of patients present resistance to antileukaemic agents and dismal prognosis. In this study, we analysed miR-125b expression in childhood ALL and evaluated its clinical utility for...

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Detalles Bibliográficos
Autores principales: Piatopoulou, Despina, Avgeris, Margaritis, Marmarinos, Antonios, Xagorari, Marieta, Baka, Margarita, Doganis, Dimitrios, Kossiva, Lydia, Scorilas, Andreas, Gourgiotis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589998/
https://www.ncbi.nlm.nih.gov/pubmed/28787435
http://dx.doi.org/10.1038/bjc.2017.256