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3-Cyanoallyl boronates are versatile building blocks in the synthesis of polysubstituted thiophenes
We report the preparation of hitherto unprecedented 3-cyanoallyl boronates using condensation of the parent α-boryl aldehyde and nitriles. The resulting allyl boronates have been used to generate a wide range of borylated thiophenes, which represent a valuable class of heterocycles in modern drug di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590094/ https://www.ncbi.nlm.nih.gov/pubmed/28936329 http://dx.doi.org/10.1039/c7sc00831g |