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Synthesis of bioactive and stabilized cyclic peptides by macrocyclization using C(sp(3))–H activation
Cyclic peptides have attracted increasing attention in recent years due to their ability to inhibit protein–protein interactions. Current strategies to prepare cyclic peptides often rely on functional amino acid side chains or the incorporation of unnatural amino acids, thus limiting their structura...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590095/ https://www.ncbi.nlm.nih.gov/pubmed/28936334 http://dx.doi.org/10.1039/c6sc05530c |