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Kinetic resolution of racemic 2-substituted 1,2-dihydroquinolines via asymmetric Cu-catalyzed borylation

A highly efficient kinetic resolution of racemic 2-substituted 1,2-dihydroquinolines via asymmetric Cu-catalyzed borylation has been realized for the first time. Under mild conditions, a variety of chiral 3-boryl-1,2,3,4-tetrahydroquinolines containing two vicinal stereogenic centers as well as the...

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Detalles Bibliográficos
Autores principales: Kong, Duanyang, Han, Suna, Wang, Rui, Li, Meina, Zi, Guofu, Hou, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590099/
https://www.ncbi.nlm.nih.gov/pubmed/28936333
http://dx.doi.org/10.1039/c7sc01556a