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Sumoylation in p27kip1 via RanBP2 promotes cancer cell growth in cholangiocarcinoma cell line QBC939

BACKGROUND: Cholangiocarcinoma is one of the deadly disease with poor 5-year survival and poor response to conventional therapies. Previously, we found that p27kip1 nuclear-cytoplasmic translocation confers proliferation potential to cholangiocarcinoma cell line QBC939 and this process is mediated b...

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Detalles Bibliográficos
Autores principales: Yang, Jun, Liu, Yan, Wang, Bing, Lan, Hongzhen, Liu, Ying, Chen, Fei, Zhang, Ju, Luo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590128/
https://www.ncbi.nlm.nih.gov/pubmed/28882106
http://dx.doi.org/10.1186/s12867-017-0100-5