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Nonstandard Finite Difference Method Applied to a Linear Pharmacokinetics Model
We extend the nonstandard finite difference method of solution to the study of pharmacokinetic–pharmacodynamic models. Pharmacokinetic (PK) models are commonly used to predict drug concentrations that drive controlled intravenous (I.V.) transfers (or infusion and oral transfers) while pharmacokineti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590451/ https://www.ncbi.nlm.nih.gov/pubmed/28952519 http://dx.doi.org/10.3390/bioengineering4020040 |