Engineering of CHO Cells for the Production of Recombinant Glycoprotein Vaccines with Xylosylated N-glycans

Xylose is a general component of O-glycans in mammals. Core-xylosylation of N-glycans is only found in plants and helminth. Consequently, xylosylated N-glycans cause immunological response in humans. We have used the F-protein of the human respiratory syncytial virus (RSV), one of the main causes of...

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Detalles Bibliográficos
Autores principales: Sandig, Grit, von Horsten, Hans Henning, Radke, Lars, Blanchard, Véronique, Frohme, Marcus, Giese, Christoph, Sandig, Volker, Hinderlich, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590453/
https://www.ncbi.nlm.nih.gov/pubmed/28952517
http://dx.doi.org/10.3390/bioengineering4020038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590453/
https://www.ncbi.nlm.nih.gov/pubmed/28952517
http://dx.doi.org/10.3390/bioengineering4020038

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