Comparative N-Glycosylation Analysis of the Fc Portions of a Chimeric Human Coagulation Factor VIII and Immunoglobulin G1

Prevention and treatment of bleeding in patients suffering from hemophilia A are inconvenient due to repeated intravenous infusions owing to the short half-life of coagulation factor VIII (FVIII) in circulation. Besides (glyco-)pegylation of the FVIII molecule, a bioengineering approach comprises th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kannicht, Christoph, Kröning, Mario, Solecka-Witulska, Barbara A., Kohla, Guido, Rosenlöcher, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590467/
https://www.ncbi.nlm.nih.gov/pubmed/28952523
http://dx.doi.org/10.3390/bioengineering4020044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590467/
https://www.ncbi.nlm.nih.gov/pubmed/28952523
http://dx.doi.org/10.3390/bioengineering4020044

Ejemplares similares