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Comparative N-Glycosylation Analysis of the Fc Portions of a Chimeric Human Coagulation Factor VIII and Immunoglobulin G1
Prevention and treatment of bleeding in patients suffering from hemophilia A are inconvenient due to repeated intravenous infusions owing to the short half-life of coagulation factor VIII (FVIII) in circulation. Besides (glyco-)pegylation of the FVIII molecule, a bioengineering approach comprises th...
Autores principales: | Kannicht, Christoph, Kröning, Mario, Solecka-Witulska, Barbara A., Kohla, Guido, Rosenlöcher, Julia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590467/ https://www.ncbi.nlm.nih.gov/pubmed/28952523 http://dx.doi.org/10.3390/bioengineering4020044 |
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