Cargando…

Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in Large-Scale Bioreactors

Successful scale-up of bioprocesses requires that laboratory-scale performance is equally achieved during large-scale production to meet economic constraints. In industry, heuristic approaches are often applied, making use of physical scale-up criteria that do not consider cellular needs or properti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuschel, Maike, Siebler, Flora, Takors, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590480/
https://www.ncbi.nlm.nih.gov/pubmed/28952507
http://dx.doi.org/10.3390/bioengineering4020027