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Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in Large-Scale Bioreactors
Successful scale-up of bioprocesses requires that laboratory-scale performance is equally achieved during large-scale production to meet economic constraints. In industry, heuristic approaches are often applied, making use of physical scale-up criteria that do not consider cellular needs or properti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590480/ https://www.ncbi.nlm.nih.gov/pubmed/28952507 http://dx.doi.org/10.3390/bioengineering4020027 |