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Quantitative comparison of the spreading and invasion of radial growth phase and metastatic melanoma cells in a three-dimensional human skin equivalent model

BACKGROUND: Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation and invasion in a 3D melanoma skin equ...

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Detalles Bibliográficos
Autores principales: Haridas, Parvathi, McGovern, Jacqui A., McElwain, Sean D.L., Simpson, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590551/
https://www.ncbi.nlm.nih.gov/pubmed/28890854
http://dx.doi.org/10.7717/peerj.3754