Molecular heterogeneity at the network level: high-dimensional testing, clustering and a TCGA case study

MOTIVATION: Molecular pathways and networks play a key role in basic and disease biology. An emerging notion is that networks encoding patterns of molecular interplay may themselves differ between contexts, such as cell type, tissue or disease (sub)type. However, while statistical testing of differe...

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Detalles Bibliográficos
Autores principales: Städler, Nicolas, Dondelinger, Frank, Hill, Steven M, Akbani, Rehan, Lu, Yiling, Mills, Gordon B, Mukherjee, Sach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590725/
https://www.ncbi.nlm.nih.gov/pubmed/28535188
http://dx.doi.org/10.1093/bioinformatics/btx322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590725/
https://www.ncbi.nlm.nih.gov/pubmed/28535188
http://dx.doi.org/10.1093/bioinformatics/btx322

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