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Molecular heterogeneity at the network level: high-dimensional testing, clustering and a TCGA case study
MOTIVATION: Molecular pathways and networks play a key role in basic and disease biology. An emerging notion is that networks encoding patterns of molecular interplay may themselves differ between contexts, such as cell type, tissue or disease (sub)type. However, while statistical testing of differe...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590725/ https://www.ncbi.nlm.nih.gov/pubmed/28535188 http://dx.doi.org/10.1093/bioinformatics/btx322 |