A right-handed signalling pathway drives heart looping in vertebrates

The majority of animals show external bilateral symmetry, precluding the observation of multiple internal left-right (L/R) asymmetries that are fundamental for organ packaging and function1,2. In vertebrates, left identity is mediated by the left-specific Nodal-Pitx2 axis that is repressed on the ri...

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Detalles Bibliográficos
Autores principales: Ocaña, Oscar H., Coskun, Hakan, Minguillón, Carolina, Murawala, Prayag, Tanaka, Elly M., Galcerán, Joan, Muñoz-Chapuli, Ramón, Nieto, M. Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590727/
https://www.ncbi.nlm.nih.gov/pubmed/28880281
http://dx.doi.org/10.1038/nature23454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590727/
https://www.ncbi.nlm.nih.gov/pubmed/28880281
http://dx.doi.org/10.1038/nature23454

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