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Lower frequency of TLR9 variant associated with protection from breast cancer among African Americans

INTRODUCTION: Toll-like receptor 9 (TLR9) is an innate immune system DNA-receptor that regulates tumor invasion and immunity in vitro. Low tumor TLR9 expression has been associated with poor survival in Caucasian patients with triple negative breast cancer (TNBC). African American (AA) patients with...

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Detalles Bibliográficos
Autores principales: Chandler, Madison R., Keene, Kimberly S., Tuomela, Johanna M., Forero-Torres, Andres, Desmond, Renee, Vuopala, Katri S., Harris, Kevin W., Merner, Nancy D., Selander, Katri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590816/
https://www.ncbi.nlm.nih.gov/pubmed/28886076
http://dx.doi.org/10.1371/journal.pone.0183832