Maternal treatment with short-chain fatty acids modulates the intestinal microbiota and immunity and ameliorates type 1 diabetes in the offspring

We recently hypothesized that the intestinal microbiota and the innate immune system play key roles in the mechanism of Kilham Rat Virus-induced type 1 diabetes in the LEW1.WR1 rat. We used this animal model to test the hypothesis that maternal therapy with short-chain fatty acids can modulate the i...

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Detalles Bibliográficos
Autores principales: Needell, James C., Ir, Diana, Robertson, Charles E., Kroehl, Miranda E., Frank, Daniel N., Zipris, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590848/
https://www.ncbi.nlm.nih.gov/pubmed/28886045
http://dx.doi.org/10.1371/journal.pone.0183786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590848/
https://www.ncbi.nlm.nih.gov/pubmed/28886045
http://dx.doi.org/10.1371/journal.pone.0183786

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